DOCK1
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
HRP
Indications d'application
Western blot: 3-4 μg/mL. Approx 150-200 kDa band seen in A431 cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
anticorps DOCK180, anticorps ced5, anticorps 9130006G06Rik, anticorps AI854900, anticorps D630004B07Rik, anticorps RGD1566072, anticorps dedicator of cytokinesis 1, anticorps dedicator of cytokinesis protein 1, anticorps dedicator of cyto-kinesis 1, anticorps DOCK1, anticorps Dock1, anticorps dock1, anticorps CpipJ_CPIJ002759
Sujet
The DOCK1 protein is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. It also functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. The GEF activity of the DOCK1 protein may be enhanced by ELMO1.Synonyms: 180 kDa protein downstream of CRK, Dedicator of cytokinesis protein 1