DOCK1 anticorps (C-Term)

N° du produit ABIN374114

L’anticorps anti-DOCK1 Polyclonal Chèvre est utilisé pour la détection de DOCK1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Porc. Il a été validé pour WB.

Aperçu rapide pour DOCK1 anticorps (C-Term) (ABIN374114)

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DOCK1 anticorps

Épitope: C-Term

Séquence: C-TTRKQTSVDS GIVQ

Specificité: This antibody detects DOCK1 at C-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_001371.1 Genename: DOCK1

Information d'application

Indications d'application: Western blot: 3-4 μg/mL. Approx 150-200 kDa band seen in A431 cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur DOCK1

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Autre désignation: DOCK1 / DOCK180

Sujet: The DOCK1 protein is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. It also functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. The GEF activity of the DOCK1 protein may be enhanced by ELMO1.Synonyms: 180 kDa protein downstream of CRK, Dedicator of cytokinesis protein 1

ID gène: 1793

NCBI Accession: NP_001371

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor