CREB3L4
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 50 kDa band observed in Human Placenta lysate(predicted MW of 40 kDa according to NP_570968). Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Prostate shows strongstaining of cytoplasm in the secretory cells of the gland. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Antigène
CREB3L4
(cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))
Androgen-induced basic leucine zipper (AIBZIP)is a transcription factor. AIbZIP is a 395 aa protein with homology to cyclic AMP-responsive element binding protein/activating transcription factor. It contains an NH(2)-terminal activation domain, a central bZIP domain, and a COOH-terminal transmembrane domain. Immunoreactive AIbZIP protein has been detected in the cytoplasm of prostatic luminal epithelial cells, full-length AIbZIP-GFP fusion proteins are localized in the cytoplasm of LNCaP cells, while a truncated form of AIbZIP lacking the putative transmembrane domain was exclusively nuclear. AIbZIP is expressed at higher levels in cancerous prostate cells compared with noncancerous prostate cells.Synonyms: Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, CREB4, Cyclic AMP-responsive element-binding protein 3-like protein 4, JAL, Transcript induced in spermiogenesis protein 40, cAMP-responsive element-binding protein 3-like protein 4, hJAL