GULP1 anticorps (C-Term)

N° du produit ABIN374220

Cet anticorps anti-GULP1 Polyclonal Chèvre (ABIN374220) détecte spécifiquement GULP1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour GULP1 anticorps (C-Term) (ABIN374220)

Antigène: GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GULP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GULP1 anticorps

Épitope: C-Term

Séquence: EGTVFCLDPL DSRC

Specificité: This antibody detetcs GULP / GULP1 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_057399.1. Genename: GULP1

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 64000. Western blot: 0.2-0.6 μg/mL. Approx 35 kDa band observed in Human Placenta lysates(calculated MW of 34.5 kDa according to NP_057399.1). Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Kidney shows staining ofcytoplasm, stronger in a selection of epithelial cells of distal convoluted tubules.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur GULP1

Antigène: GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1))

Autre désignation: GULP1 / CED6

Sujet: The prompt clearance of cells undergoing apoptosis is critical during embryonic development, normal tissue turnover, as well as inflammation and autoimmunity. CED6 and its human homologue gulp, encode an adapter protein, whose function in engulfment. The upstream and downstream components of CED6 mediated signaling are not known. Recently, CED1 has been shown to encode a transmembrane protein on phagocytic cells, with two functional sequence motifs in its cytoplasmic tail that are important for engulfment.Synonyms: CED-6, Cell death protein 6 homolog, PTB domain adapter protein CED-6, PTB domain-containing engulfment adapter protein 1

ID gène: 51454

NCBI Accession: NP_057399

UniProt: Q9UBP9