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HSPB8 anticorps (C-Term)

Cet anticorps Chèvre Polyclonal détecte spécifiquement HSPB8 dans WB et EIA. Il présente une réactivité envers Humain.
N° du produit ABIN374275

Aperçu rapide pour HSPB8 anticorps (C-Term) (ABIN374275)

Antigène

Voir toutes HSPB8 Anticorps
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivité

  • 90
  • 36
  • 25
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 74
  • 18
  • 1
Chèvre

Clonalité

  • 68
  • 25
Polyclonal

Conjugué

  • 47
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HSPB8 est non-conjugé

Application

  • 71
  • 36
  • 28
  • 26
  • 19
  • 18
  • 13
  • 13
  • 8
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 21
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    Séquence

    NELPQDSQEV TCT

    Specificité

    This antibody detects Heat shock protein beta-8 (HSPB8) at C-term.

    Réactivité croisée (Details)

    Species reactivity (tested):Human

    Purification

    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

    Immunogène

    Peptide from C Terminus of the protein sequence according to NP_055180.1 Genename: HSPB8
  • Indications d'application

    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1 μg/mL. Approx 20-25 kDa band seen in human skeletal muscle lysate[Predicted MW of approx.25 kDa according to NP_055180].
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
  • Antigène

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    Autre désignation

    HSPB8 / HSP22

    Sujet

    Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).Synonyms: Alpha-crystallin C chain, CRYAC, E2-induced gene 1 protein, E2IG1, Heat shock protein beta-8, Protein kinase H11, Small stress protein-like protein HSP22

    ID gène

    26353

    NCBI Accession

    NP_055180

    UniProt

    Q9UJY1
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