HSPB8 anticorps (C-Term)
Aperçu rapide pour HSPB8 anticorps (C-Term) (ABIN374275)
Antigène
Voir toutes HSPB8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Séquence
- NELPQDSQEV TCT
-
Specificité
- This antibody detects Heat shock protein beta-8 (HSPB8) at C-term.
-
Réactivité croisée (Details)
- Species reactivity (tested):Human
-
Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
-
Immunogène
- Peptide from C Terminus of the protein sequence according to NP_055180.1 Genename: HSPB8
-
-
-
-
Indications d'application
-
Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1 μg/mL. Approx 20-25 kDa band seen in human skeletal muscle lysate[Predicted MW of approx.25 kDa according to NP_055180].
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
-
-
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
-
Autre désignation
- HSPB8 / HSP22
-
Sujet
- Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).Synonyms: Alpha-crystallin C chain, CRYAC, E2-induced gene 1 protein, E2IG1, Heat shock protein beta-8, Protein kinase H11, Small stress protein-like protein HSP22
-
ID gène
- 26353
-
NCBI Accession
- NP_055180
-
UniProt
- Q9UJY1
Antigène
-