SETDB2 anticorps (N-Term)

N° du produit ABIN374283

Cet anticorps anti-SETDB2 Polyclonal Chèvre (ABIN374283) détecte spécifiquement SETDB2 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour SETDB2 anticorps (N-Term) (ABIN374283)

Antigène: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SETDB2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SETDB2 anticorps

Épitope: N-Term

Séquence: GEKNGDAKTF WME-C

Specificité: This antibody is expected to recognize both reported isoforms (NP_114121.2, NP_001153780.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Porcine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogène: Synthetic peptide (GEKNGDAKTFWME-C) from the N-Terminus of the protein sequence according to NP_114121.2, NP_001153780.1. Genename: SETDB2

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 1000. Western blot: 0.3-1 μg/mL. Approx 80 kDa band observed in human heart lysates(calculated MW of 81.0 kDa according to NP_114121.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SETDB2

Antigène: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Autre désignation: SETDB2 / CLLD8

Sujet: Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity.Synonyms: C13orf4, Chronic lymphocytic leukemia deletion region gene 8 protein, Histone-lysine N-methyltransferase SETDB2, KMT1F, Lysine N-methyltransferase 1F, SET domain bifurcated 2

Poids moléculaire: 81.9 kDa (NP_114121.1)

ID gène: 83852

NCBI Accession: NP_114121

UniProt: Q96T68