CDYL anticorps (C-Term)
Aperçu rapide pour CDYL anticorps (C-Term) (ABIN374294)
Antigène
Voir toutes CDYL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- C-SMLKYLQRKI DEF
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Specificité
- This antibody detects CDYL at C-term.
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Réactivité croisée (Details)
- Species reactivity (expected):Mouse, Rat, Dog, CowSpecies reactivity (tested):Human
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Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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Immunogène
- Peptide from C Terminus of the protein sequence according to NP_004815.3, NP_001137442.1, NP_001137443.1 Genename: CDYL
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Indications d'application
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Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 75 kDa band observed in Human Testes lysates (calculatedMW of 66.5 kDa according to NP_004815.2). The observed molecular weight corresponds toearlier findings in literature with different antibodies (Lahn et al , Proc Natl Acad Sci U S A.2002 Jun 25,99(13): 8707-12, PMID: 12072557).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- CDYL (Chromodomain Protein, Y-Like (CDYL))
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Autre désignation
- CDYL
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Sujet
- Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone methylation. Multiple proteins are encoded by transcript variants of this gene.Synonyms: CDY-like, CDYL1, Chromodomain Y-like protein
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ID gène
- 9425
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NCBI Accession
- NP_004815
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UniProt
- Q9Y232
Antigène
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