PPP1R8 anticorps (C-Term)

N° du produit ABIN374344

Détail du produit anti-PPP1R8 anticorps

Antigène: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-EAWPGKKPTP SLLI

Specificité: This antibody detects NIPP-1 at C-term. It is expected to recognise all three Human isoforms of this protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_002704.1, NP_054829.2, NP_612568.1. Genename: PPP1R8

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-2 μg/mL. Approx 40 kDa band observed in Human Lung and H460 cellextracts (predicted MW of 40 kDa according to NP_054829).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PPP1R8

Antigène: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Autre désignation: NIPP-1 (PPP1R8 Produits)

Synonymes: anticorps ARD-1, anticorps ARD1, anticorps NIPP-1, anticorps NIPP1, anticorps PRO2047, anticorps 6330548N22Rik, anticorps AU044684, anticorps PPP1R8, anticorps ard-1, anticorps ard1, anticorps nipp-1, anticorps nipp1, anticorps ppp1r8, anticorps si:ch211-206a7.1, anticorps protein phosphatase 1 regulatory subunit 8, anticorps protein phosphatase 1, regulatory subunit 8, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 8, anticorps protein phosphatase 1, regulatory subunit 8b, anticorps protein phosphatase 1 regulatory subunit 8 L homeolog, anticorps protein phosphatase 1, regulatory subunit 8a, anticorps protein phosphatase 1 regulatory subunit 8 S homeolog, anticorps PPP1R8, anticorps Ppp1r8, anticorps ppp1r8b, anticorps ppp1r8.L, anticorps ppp1r8a, anticorps ppp1r8.S

Sujet: Inhibitor subunit of the major nuclear protein phosphatase 1 (PP1). It has RNA binding activity but does not cleave RNA and may target PP1 to RNA associated substrates. May also be involved in pre mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.Synonyms: ARD1, NIPP1, Nuclear inhibitor of protein phosphatase 1, PPP1R8

ID gène: 5511

NCBI Accession: NP_002704

UniProt: Q12972