PARD6A anticorps (C-Term)

N° du produit ABIN374388

Cet anticorps anti-PARD6A Polyclonal Chèvre (ABIN374388) détecte spécifiquement PARD6A dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PARD6A anticorps (C-Term) (ABIN374388)

Antigène: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PARD6A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PARD6A anticorps

Épitope: C-Term

Séquence: C-GSRIRGDGSG FSL

Specificité: This antibody detects PARD6A at C-term. It is expected to recognise both reported isoforms (NP_058644.1, NP_001032358.1).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Syntehtic Peptide from C-Terminus of Human PARD6A Genename: PARD6A

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 8000. Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Pancreas, shows strongcytoplasmic staining in rare cells of intralobular ducts. Recommended concentration,10 μg/mL. Also tested in paraffin embedded Human Heart where it shows speckled stainingon myocardial fibres in transverse section.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PARD6A

Antigène: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Autre désignation: PARD6A

Sujet: PAR6 is a cell membrane protein involved in cell polarization and asymmetrical cell division processes as part of a multi protein complex. It is thought to be involved in the invasive phenotype that is associated with metastatic carcinomas, playing a role in the epithelial to mesenchymal transition (EMT). PAR6 is also thought to be involved in the formation of epithelial tight junctions. PAR6 contains a semi Cdc42/Rac interactive binding (CRIB) domain and a PDZ (PSD95/Discs-large/ZO1) domain, and several different PAR6 isoforms have been identified.Synonyms: PAR-6, PAR-6 alpha, PAR-6A, PAR6A, PAR6C, Partitioning defective 6 homolog alpha, TIP-40, Tax interaction protein 40

ID gène: 50855

NCBI Accession: NP_058644

UniProt: Q9NPB6

Pathways: Cell-Cell Junction Organization