NIR1 anticorps (C-Term)

N° du produit ABIN374424

Cet anticorps anti-NIR1 est un anticorps Chèvre Polyclonal détectant NIR1 dans WB et IHC (p). Adapté pour Humain, Chien et Souris.

Aperçu rapide pour NIR1 anticorps (C-Term) (ABIN374424)

Antigène: NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

Reactivité: Humain, Chien, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NIR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NIR1 anticorps

Épitope: C-Term

Séquence: C-SWARGPPKFE SVP

Specificité: This antibody detects NIR1 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, DogSpecies reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_112497.2, NP_001159438.1. Genename: PITPNM3

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 16000. Western blot: Preliminary experiments gave an approx 50 kDa band in Human Heart lysatesafter 0.1 μg/mL antibody staining. The 50 kDa band was successfully blocked by incubationwith the immunizing peptide. Immunohistochemistry: 5-10 μg/mL. In paraffin embeddedHuman Cerebral Cortex shows strong staining of cytoplasm in several neuronal cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur NIR1

Antigène: NIR1 (PITPNM3) (PITPNM Family Member 3 (PITPNM3))

Autre désignation: PITPNM3

Sujet: This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Membrane-associated phosphatidylinositol transfer protein 3, NIR-1, NIR1, PITPNM 3, Phosphatidylinositol transfer protein, Pyk2 N-terminal domain-interacting receptor 1, membrane-associated 3

ID gène: 83394

NCBI Accession: NP_112497

UniProt: Q9BZ71