FTCD anticorps (N-Term)

N° du produit ABIN374453

L’anticorps anti-FTCD Polyclonal Chèvre est utilisé pour la détection de FTCD dans des échantillons de Humain, Souris et Porc. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour FTCD anticorps (N-Term) (ABIN374453)

Antigène: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reactivité: Humain, Souris, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FTCD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-FTCD anticorps

Épitope: N-Term

Séquence: SQLVECVPNF SEGKNQ

Specificité: This antibody recognizes 58K Golgi protein at N-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Pig.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the N-Terminus of the protein sequence according to NP_006648.1, NP_996848.1. Genename: FTCD

Information d'application

Indications d'application: Peptide ELISA: Detection Limit: 1/64000. Western blot: 0.03-0.5 μg/mL. Detects a 55-60 kDa band in Human Liver lysate (PredictedMolecular Weight: 58.0 kDa). Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Liver shows distinct staining of membranes and cytoplasm ina selection of hepatocytes.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FTCD

Antigène: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Autre désignation: 58K Golgi Protein

Sujet: 58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1

ID gène: 10841, 9606

UniProt: O95954