FTCD anticorps (Internal Region)

N° du produit ABIN374454

Cet anticorps anti-FTCD Polyclonal Chèvre (ABIN374454) détecte spécifiquement FTCD dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Porc.

Aperçu rapide pour FTCD anticorps (Internal Region) (ABIN374454)

Antigène: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reactivité: Humain, Souris, Rat, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FTCD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-FTCD anticorps

Épitope: Internal Region

Séquence: CLREQGRGKD QPGRL

Specificité: This antibody recognizes 58KGolgi protein (Internal).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat and Pig.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_006648.1, NP_996848.1 Genename: FTCD

Information d'application

Indications d'application: Peptide ELISA: Antibody Detection Limit: 1/64000. Western blot: 0.01-0.03 μg/mL. Detects a approx. 60 kDa band in Human Liver lysates (calculatedMW of 58.0 kDa according to NP_006648.1 and NP_996848.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FTCD

Antigène: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Autre désignation: 58K Golgi Protein

Sujet: 58K Golgi protein antibodies are excellent for use as markers for the Golgi complex. The 58K Golgi protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency, also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.Synonyms: FTCD, Formimidoyltransferase-cyclodeaminase, Formiminotransferase-cyclodeaminase, Golgi Marker 58K, Golgi marker, LCHC1

ID gène: 10841, 9606

UniProt: O95954