PPY anticorps (Internal Region)
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- Antigène Voir toutes PPY Anticorps
- PPY (Pancreatic Polypeptide (PPY))
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Épitope
- Internal Region
- Reactivité
- Humain, Rat, Souris, Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PPY est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Séquence
- C-TRPRYGKRHK EDT
- Specificité
- This antibody recognizes Pancreatic prohormone.
- Réactivité croisée (Details)
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Species reactivity (expected):Rat and Canine (Dog).
Species reactivity (tested):Human, Mouse. - Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Synthetic peptide from the internal region of the protein sequence according to NP_002713.1. Genename: PPY
- Top Product
- Discover our top product PPY Anticorps primaire
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- Indications d'application
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Peptide ELISA: Antibody Detection Limit Dilution: 1/32000. Western Blot: Preliminary experiments gave an approx 35-38 kDa band in human pancreaslysates after 1 μg/mL antibody staining. Please note that currently we cannot find anexplanation in the literature for the band we observe given the calculated size of 10.8 kDaaccording to NP_002713.1. The 38 kDa band was successfully blocked by incubation withthe immunizing peptide. Immunohistochemistry: 3 μg/mL. In paraffin embedded human pancreas, shows strong cytoplasmic staining of rare cellslocated at the periphery of islets of Langerhans.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PPY (Pancreatic Polypeptide (PPY))
- Autre désignation
- Pancreatic Prohormone (PPY Produits)
- Synonymes
- anticorps PPY, anticorps PNP, anticorps PP, anticorps AV061413, anticorps IGSPP, anticorps pancreatic polypeptide, anticorps peptide YY, anticorps PPY, anticorps Ppy, anticorps PYY
- Sujet
- Pancreatic hormone (PPY) is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.Synonyms: Obinepitide, PNP, PPY, Pancreatic polypeptide
- ID gène
- 5539
- NCBI Accession
- NP_002713
- UniProt
- P01298
- Pathways
- Feeding Behaviour
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