Caveolin-1 anticorps (Internal Region)
Aperçu rapide pour Caveolin-1 anticorps (Internal Region) (ABIN374578)
Antigène
Voir toutes Caveolin-1 (CAV1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- This antibody recognizes Caveolin-1. No cross-reactivity expected to Caveolin-2 and Caveolin-3.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Porcine.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography
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Immunogène
- Synthetic peptide from Human CAV1 / Caveolin. Peptide with sequence C-DELSEKQVYDAH, from the internal region of Caveolin 1 Genename: CAV1
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Indications d'application
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Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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Autre désignation
- Caveolin-1
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Sujet
- Caveolin 1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulator of the Ras-p42/44 MAP kinase cascade.Synonyms: CAV1
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ID gène
- 857, 9606
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UniProt
- Q03135
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Pathways
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
Antigène
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