CBX5 anticorps (Internal Region)

N° du produit ABIN374617

Détail du produit anti-CBX5 anticorps

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Épitope: Internal Region

Reactivité: Humain, Souris, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody recognizes Human Chromobox protein homolog 5 (CBX5).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence C-NKRKSNFSNSADDIK, from the internal region of the protein sequence according to NP_036249.1, NP_001120793.1, NP_001120794.1. .Remarks: Variants (NP_036249.1, NP_001120793.1, NP_001120794.1) encode the same protein

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CBX5

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Autre désignation: CBX5 (CBX5 Produits)

Synonymes: anticorps HP1, anticorps HP1A, anticorps id:ibd2026, anticorps wu:fc63e02, anticorps wu:fe47g12, anticorps wu:fi03h05, anticorps zgc:158601, anticorps CBX5, anticorps cbx5, anticorps MGC64354, anticorps 2610029O15Rik, anticorps C75991, anticorps Hp1a, anticorps Hp1alpha, anticorps chromobox 5, anticorps chromobox homolog 5 (HP1 alpha homolog, Drosophila), anticorps chromobox 5 S homeolog, anticorps CBX5, anticorps cbx5, anticorps Cbx5, anticorps cbx5.S

Sujet: HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.Synonyms: Chromobox protein homolog 5, HP1 alpha, HP1-alpha, HP1A, Heterochromatin protein 1 homolog alpha, p25

Poids moléculaire: 22.2 kDa (NP_036249.1)

ID gène: 23468, 9606

UniProt: P45973