UCP1 anticorps (C-Term)
Aperçu rapide pour UCP1 anticorps (C-Term) (ABIN374628)
Antigène
Voir toutes UCP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- C-EQLKRELSKS RQ
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Specificité
- This antibody recognizes Thermogenin (UCP1).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human. -
Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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Immunogène
- Peptide with sequence from the C Terminus of the protein sequence according to NP_068605.1
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Indications d'application
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Peptide ELISA: 1/128000. Western Blot: 0.1 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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Autre désignation
- SLC25A7 / UCP1
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Sujet
- The uncoupling proteins (UCPs) are mitochondrial inner membrane proteins that are considered to be transporters functioning as enzymatic uncouplers of oxidative phosphorylation. They are capable of returning protons pumped by the respiratory chain to the mitochondrial matrix. Uncoupling proteins currently comprise UCP1, UCP2, UCP3, UCP4, and UCP5. UCP1 is a 32 kDa protein that is active as a proton channel forming dimer. It can bind purine nucleotides and is capable of being stimulated by fatty acids.Synonyms: Mitochondrial brown fat uncoupling protein 1, Solute carrier family 25 member 7, Thermogenin, UCP 1, UCP-1
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ID gène
- 7350, 9606
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UniProt
- P25874
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Pathways
- Proton Transport, Brown Fat Cell Differentiation
Antigène
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