CHRM1 anticorps (C-Term)
Aperçu rapide pour CHRM1 anticorps (C-Term) (ABIN374726)
Antigène
Voir toutes CHRM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody reacts to M1 mAChR / CHRM1.
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the protein sequence
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Indications d'application
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
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Autre désignation
- Muscarinic Acetylcholine Receptor M1
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Sujet
- The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinic receptors are so called as they are more sensitive to the effects of the alkaloid muscarine, rather than nicotine.Synonyms: CHRM1, mAChR M1, mAChR-M1
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ID gène
- 1128
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NCBI Accession
- NP_000729
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UniProt
- P11229
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Pathways
- Synaptic Membrane
Antigène
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