SV2A anticorps (Internal Region)

N° du produit ABIN374729

L’anticorps Chèvre Polyclonal anti-SV2A a été validé pour WB. Il convient pour détecter SV2A dans des échantillons de Humain, Rat, Souris et Chien.

Aperçu rapide pour SV2A anticorps (Internal Region) (ABIN374729)

Antigène: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Reactivité: Humain, Rat, Souris, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SV2A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SV2A anticorps

Épitope: Internal Region

Specificité: This antibody recognizes SV2A.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Human, Canine.
Species reactivity (tested):Rat.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-TVELYPSDKRTTA, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 80 kDa band observed in rat brain lysates (calculatedMW of 82.0 kDa according to NP_476558.1 (rat)). An additonal band of unknown identitywas also consistently observed at 20 kDa. This band was successfully blocked byincubation with the immunising peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SV2A

Antigène: SV2A (Synaptic Vesicle Glycoprotein 2A (SV2A))

Autre désignation: SV2A

Sujet: SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern. The highest expression levels were observed in phylogenetically old brain areas like pallidum, the midbrain and the olfactory bulb. SV2A is probably involved in the maintenance of a pool of synaptic vesicles competent for calcium-stimulated exocytosis. SV2A is a highly glycosylated synaptic vesicle protein with homology to transmembrane transporters.Synonyms: KIAA0736, Synaptic vesicle glycoprotein 2A

ID gène: 9900

NCBI Accession: NP_055664

UniProt: Q7L0J3