ALOX5 anticorps (C-Term)

N° du produit ABIN374732

Détail du produit anti-ALOX5 anticorps

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX5 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to Arachidonate 5-lipoxygenase.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-ERNKKKQLPYYYLSPD, from the C Terminus of the protein sequence Genename: ALOX5

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ALOX5

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Autre désignation: ALOX5 / LOG5 (ALOX5 Produits)

Synonymes: anticorps 5-LO, anticorps 5-LOX, anticorps 5LPG, anticorps LOG5, anticorps 5LO, anticorps 5LX, anticorps AI850497, anticorps F730011J02, anticorps LOX5A, anticorps si:dkey-194n13.2, anticorps lox5, anticorps arachidonate 5-lipoxygenase, anticorps arachidonate 5-lipoxygenase a, anticorps Arachidonate 5-lipoxygenase, anticorps ALOX5, anticorps Alox5, anticorps alox5a, anticorps AFUA_4G02770, anticorps AOR_1_1362014, anticorps lox5

Sujet: The enzyme 5 Lipoxygenase (5 LO) plays a key role in regulating the production of leukotrienes (LTs). Overproduction of LTs contributes to several diseases, most notably chronic inflammatory diseases, including asthma, fibrosis and atherosclerosis. Recent work has demonstrated that the activity of 5 LO is regulated by PKA phosphorylation of serine 523 in 5 LO. Under normal conditions, this phosphorylation may be important in limiting inflammation. Abnormal signaling through cAMP and PKA, then, could contribute to a variety of diseases, including those characterized by chronic inflammation.Synonyms: 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase

ID gène: 240, 9606

UniProt: P09917