LPIN3 anticorps (Internal Region)

N° du produit ABIN374744

L’anticorps anti-LPIN3 Polyclonal Chèvre est utilisé pour la détection de LPIN3 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour LPIN3 anticorps (Internal Region) (ABIN374744)

Antigène: LPIN3 (Lipin 3 (LPIN3))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp LPIN3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LPIN3 anticorps

Épitope: Internal Region

Specificité: This antibody reacts to Lipin 3.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-KPKQKEDAVATD, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/64000. Western Blot: 0.1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LPIN3

Antigène: LPIN3 (Lipin 3 (LPIN3))

Autre désignation: Lipin-3

Sujet: Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3).Synonyms: LIPN3L, LPIN3, Lipin-3-like, Lipin3

ID gène: 64900, 9606

UniProt: Q9BQK8