DISC1 anticorps (Internal Region)

N° du produit ABIN374852

L’anticorps anti-DISC1 Polyclonal Chèvre est utilisé pour la détection de DISC1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour DISC1 anticorps (Internal Region) (ABIN374852)

Antigène: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DISC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DISC1 anticorps

Épitope: Internal Region

Specificité: This antibody reacts to DISC1. This antibody is expected to recognise isoforms L and Lv only.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-HSEDKRKTPLKVLE, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DISC1

Antigène: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Autre désignation: DISC1

Sujet: DISC1 (disrupted in schizophrenia 1) is a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. DISC1 is a multifunctional protein that is involved in neurite outgrowth and cortical development, through its interaction with proteins of the centrosome and cytoskeletal system, and is implicated in schizophrenia. Regions of the primate brain which express DISC1, including the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, are reported to be involved in schizophrenia in humans.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457

ID gène: 27185

NCBI Accession: NP_001012975

UniProt: Q9NRI5

Pathways: Regulation of Cell Size