ADH5 anticorps (Internal Region)

N° du produit ABIN374869

Détail du produit anti-ADH5 anticorps

Antigène: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ADH5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-KKIKVDEFVT HN

Specificité: This antibody detects Alcohol Dehydrogenase 5 (ADH5).

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Pig, Bovine.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_000662.3 Genename: ADH5

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 1000. Western blot: 1-3 μg/mL. Customer's experiments gave a band at approx 38 kDa in MouseLymphocyte lysates (calculated MW of 39.8 kDa according to Human NP_000662.3 and39.8 kDa according to Mouse NP_031436.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ADH5

Antigène: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Autre désignation: Alcohol Dehydrogenase 5 (ADH5) (ADH5 Produits)

Synonymes: anticorps ADH2, anticorps ADH-3, anticorps ADHX, anticorps FALDH, anticorps FDH, anticorps GSH-FDH, anticorps GSNOR, anticorps ADH1C, anticorps ADH3, anticorps wu:fb60b11, anticorps Adh-5, anticorps Adh3, anticorps adh-3, anticorps adh3, anticorps adh5, anticorps adhx, anticorps fdh, anticorps gsnor, anticorps ADH4, anticorps ADH5, anticorps alcohol dehydrogenase 1B (class I), beta polypeptide, anticorps alcohol dehydrogenase 5 (class III), chi polypeptide, anticorps alcohol dehydrogenase 5, anticorps alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog, anticorps alcohol dehydrogenase class-3, anticorps ADH1B, anticorps ADH5, anticorps adh5, anticorps Adh5, anticorps adh5.L, anticorps LOC101112223

Sujet: The ADH5 gene encodes glutathione dependent formaldehyde dehydrogenase or class III alcohol dehydrogenase chi subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, retinol, ethanol and other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class III alcohol dehydrogenase is a homodimer composed of 2 chi subunits. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long chain primary alcohols and for oxidation of S hydroxymethyl glutathione, a spontaneous adduct between formaldehyde and glutathione. The enzyme is an important component of cellular metabolism for the elimination of formaldehyde, which is a potent irritant and sensitizing agent that causes rhinitis, lacrymation, contact dermatitis and pharyngitis.Synonyms: Alcohol dehydrogenase class 3 chi chain, Glutathione-dependent formaldehyde dehydrogenase, S-(hydroxymethyl)glutathione dehydrogenase

Poids moléculaire: 39.7 kDa according to NP_000662.3.

ID gène: 128, 9606

UniProt: P11766