EGR4 anticorps (Internal Region)

N° du produit ABIN374881

Détail du produit anti-EGR4 anticorps

Antigène: EGR4 (Early Growth Response 4 (EGR4))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp EGR4 est non-conjugé

Application: Western Blotting (WB)

Séquence: NCGSQGDYQA APE

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_001956.2

Information d'application

Indications d'application: Peptide ELISA: limit dilution 1: 4000. Western blot: 0.3-1 μg/mL. Approx 50 kDa band observed in Human Brain (Cerebellum andFrontal Cortex) lysates (calculated MW of 50.0 kDa according to NP_001956.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur EGR4

Antigène: EGR4 (Early Growth Response 4 (EGR4))

Autre désignation: EGR4 (EGR4 Produits)

Synonymes: anticorps EGR4, anticorps NGFI-C, anticorps NGFIC, anticorps PAT133, anticorps NGF1-C, anticorps pAT133, anticorps Egr4l1, anticorps early growth response 4, anticorps EGR4, anticorps Egr4

Sujet: EGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.Synonyms: AT133, EGR-4, Early growth response protein 4, NGFI-C, NGFIC, PAT133

ID gène: 9606

UniProt: Q05215