PC anticorps (Internal Region)

N° du produit ABIN374944

Cet anticorps Chèvre Polyclonal détecte spécifiquement PC dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Boeuf (Vache) et Chien.

Aperçu rapide pour PC anticorps (Internal Region) (ABIN374944)

Antigène: PC (Pyruvate Carboxylase (PC))

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PC anticorps

Épitope: Internal Region

Séquence: C-KFKEVKKAYV EANQ

Specificité: Recognizes Pyruvate Carboxylase (PC).

Réactivité croisée (Details): Species reactivity (expected):Human, Rat, Canine, Bovine, Porcine.
Species reactivity (tested):Mouse.

Purification: Affinity Chromatography

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_000911.2, NP_001035806.1 and NP_071504.2.

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PC

Antigène: PC (Pyruvate Carboxylase (PC))

Autre désignation: Pyruvic Carboxylase (PC)

Sujet: Pyruvate Carboxylase (PC, PCB) requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. PCB is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.Synonyms: PCB, Pyruvate carboxylase mitochondrial

Poids moléculaire: 130kDa (NP_000911.2, NP_001035806.1 and NP_071504.2).

ID gène: 5091, 9606

UniProt: P11498