ERP29 anticorps (C-Term)

N° du produit ABIN375036

Cet anticorps anti-ERP29 est un anticorps Chèvre Polyclonal détectant ERP29 dans WB. Adapté pour Humain, Rat, Souris, Chien, Boeuf (Vache) et Porc.

Aperçu rapide pour ERP29 anticorps (C-Term) (ABIN375036)

Antigène: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ERP29 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ERP29 anticorps

Épitope: C-Term

Specificité: This antibody reacts to ERP29.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-EKNKMSDGKKEELQ, from the C-Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ERP29

Antigène: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Autre désignation: ERP29

Sujet: Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.Synonyms: C12orf8, ERp28, ERp31, Endoplasmic reticulum protein ERp29

ID gène: 10961

NCBI Accession: NP_006808

UniProt: P30040