Lactoferrin anticorps (Internal Region)

N° du produit ABIN375038

Il existe 1 publication pour ce produit. L’anticorps anti-Lactoferrin Polyclonal Chèvre est utilisé pour la détection de Lactoferrin dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour Lactoferrin anticorps (Internal Region) (ABIN375038)

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Lactoferrin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Lactoferrin anticorps

Épitope: Internal Region

Séquence: C-ENYKSQQSSD PDP

Specificité: This antibody detects Lactotransferrin (Internal).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002334.2. Genename: LTF

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.05 - 0.2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Lactoferrin (ABIN375038)

de la Rosa, Yang, Tewary, Varadhachary, Oppenheim: "Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6868-76, (2008) (PubMed).

Détails sur Lactoferrin

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Autre désignation: Lactotransferrin

Sujet: Lactoferrin is an 80 kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

ID gène: 4057, 9606

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis