Lactoferrin anticorps (Internal Region)

N° du produit ABIN375038

Détail du produit anti-Lactoferrin anticorps

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Lactoferrin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-ENYKSQQSSD PDP

Specificité: This antibody detects Lactotransferrin (Internal).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002334.2. Genename: LTF

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.05 - 0.2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Lactoferrin (ABIN375038)

de la Rosa, Yang, Tewary, Varadhachary, Oppenheim: "Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 10, pp. 6868-76, (2008) (PubMed).

Détails sur Lactoferrin

Antigène: Lactoferrin (LTF) (Lactotransferrin (LTF))

Autre désignation: Lactotransferrin (LTF Produits)

Synonymes: anticorps LTF, anticorps GIG12, anticorps HLF2, anticorps LF, anticorps Lf, anticorps Csp82, anticorps MMS10R, anticorps Ms10r, anticorps PLF, anticorps TFEW, anticorps conalbumin, anticorps lactotransferrin, anticorps transferrin, anticorps transferrin (ovotransferrin), anticorps LTF, anticorps CpipJ_CPIJ000114, anticorps TF, anticorps Ltf

Sujet: Lactoferrin is an 80 kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

ID gène: 4057, 9606

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis