FKBP4 anticorps (C-Term)
Aperçu rapide pour FKBP4 anticorps (C-Term) (ABIN375084)
Antigène
Voir toutes FKBP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody reacts to FKBP4 / FKBP52.
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Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence C-DHPTDTEMKEEQKSN, from the C Terminus of the protein sequence
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Indications d'application
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Peptide ELISA: 1/8000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0,5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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Autre désignation
- FKBP4
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Sujet
- FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase. It binds to the immunosuppressants FK506 and rapamycin which block distinct steps in intracellular signaling pathways. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.Synonyms: 52 kDa FK506-binding protein, FK506-binding protein 4, FKBP52 protein, FKBP59, HBI, HSP-binding immunophilin, PPIase, Peptidyl-prolyl cis-trans isomerase, Rotamase, p59 protein
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ID gène
- 2288
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NCBI Accession
- NP_002005
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UniProt
- Q02790
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Antigène
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