FAIM anticorps (Internal Region)

N° du produit ABIN375120

Détail du produit anti-FAIM anticorps

Antigène: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody reacts to all reported isoforms of FAIM1.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-KKYMEDRSKTTN, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FAIM

Antigène: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Autre désignation: FAIM (FAIM Produits)

Synonymes: anticorps FAIM1, anticorps FAIM, anticorps faim, anticorps zgc:92712, anticorps zgc:92723, anticorps Fas apoptotic inhibitory molecule, anticorps Fas apoptotic inhibitory molecule L homeolog, anticorps Fas apoptotic inhibitory molecule b, anticorps Fas apoptotic inhibitory molecule a, anticorps FAIM, anticorps Faim, anticorps faim, anticorps faim.L, anticorps Tsp_00038, anticorps faimb, anticorps faima

Sujet: FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1

ID gène: 55179, 9606

UniProt: Q9NVQ4