CST3 anticorps (Internal Region)

N° du produit ABIN375142

Cet anticorps Chèvre Polyclonal détecte spécifiquement CST3 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CST3 anticorps (Internal Region) (ABIN375142)

Antigène: CST3 (Cystatin C (CST3))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CST3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CST3 anticorps

Épitope: Internal Region

Séquence: C-SVEEEGVRRA LD

Specificité: This antibodyrecognizes CST3 / cystatin C.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_000090.1. Genename: CST3

Information d'application

Indications d'application: Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CST3

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: Cystatin-C

Sujet: Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. Cystatin C (Cystatin 3) , a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.Synonyms: CST3, Cystatin C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin

ID gène: 1471

NCBI Accession: NP_000090

UniProt: P01034