Acylglycerol Kinase anticorps (C-Term)

N° du produit ABIN375166

Cet anticorps Chèvre Polyclonal détecte spécifiquement Acylglycerol Kinase dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Acylglycerol Kinase anticorps (C-Term) (ABIN375166)

Antigène: Acylglycerol Kinase (AGK)

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Acylglycerol Kinase est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Acylglycerol Kinase anticorps

Épitope: C-Term

Specificité: This antibody reacts to Acylglycerol kinase.

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence CDPRKREQMLTSP, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Acylglycerol Kinase

Antigène: Acylglycerol Kinase (AGK)

Autre désignation: AGK / MULK

Sujet: Acylglycerol Kinase is a lipid kinase whose function is to phosphorylate monoacylglycerol to form lysophosphatidic acid (LPA) and diacylglycerol to form phosphatidic acid (PA). It does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and of the downstream MAPK signaling pathway, thus leading to increased cell growth. It is overexpressed in prostate cancer, where it may play a role in initiation and progression. Two different isoform are known.Synonyms: Acylglycerol kinase, Multiple substrate lipid kinase

ID gène: 55750

NCBI Accession: NP_060708

UniProt: Q53H12