BDKRB1 anticorps (Internal Region)

N° du produit ABIN375179

Détail du produit anti-BDKRB1 anticorps

Antigène: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp BDKRB1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Bradykinin receptor B1.

Purification: Affinity chromatography

Immunogène: Peptide with sequence KVWELYKQCTPK, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/1000. Western Blot: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-BDKRB1 (ABIN375179)

Wu, Roks, Leijten, Garrelds, Musterd-Bhaggoe, van den Bogaerdt, de Maat, Simoons, Danser, Oeseburg: "Genetic variation and gender determine bradykinin type 1 receptor responses in human tissue: implications for the ACE-inhibitor-induced effects in patients with coronary artery disease." dans: Clinical science (London, England : 1979), Vol. 126, Issue 6, pp. 441-9, (2014) (PubMed).

Détails sur BDKRB1

Antigène: BDKRB1 (Bradykinin Receptor B1 (BDKRB1))

Autre désignation: BDKRB1 (BDKRB1 Produits)

Synonymes: anticorps bdkrb2, anticorps LOC100230525, anticorps B1BKR, anticorps B1R, anticorps BKB1R, anticorps BKR1, anticorps BRADYB1, anticorps BKR, anticorps Bdkrb, anticorps b1bkr, anticorps bradykinin receptor B1, anticorps bradykinin receptor, beta 1, anticorps bdkrb1, anticorps BDKRB1, anticorps Bdkrb1

Sujet: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Bradykinin B1 receptor is generally only minimally expressed under normal physiological conditions, but the expression is induced rapidly under pathologic conditions such as ischemia, atheromatous disease, or exposure to inflammatory cytokines.Synonyms: B1 bradykinin receptor, B1R, BK-1 receptor, BKB1R, BKR1, BRADYB1, Bradykinin B1 Receptor

ID gène: 623

NCBI Accession: NP_000701

UniProt: P46663

Pathways: ACE Inhibitor Pathway