H2-D1 anticorps

N° du produit ABIN375490

Cet anticorps Souris Monoclonal détecte spécifiquement H2-D1 dans FACS, IP, CMCD, BR et IHC (fro). Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour H2-D1 anticorps (ABIN375490)

Antigène: H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp H2-D1 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Complement Mediated Cell Depletion (CMCD), Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 28-14-8

Détail du produit anti-H2-D1 anticorps

Fonction: Mouse Anti-Mouse H-2Db-LE/AF

Specificité: Mouse H-2Db

Attributs du produit: Low Endotoxin/Azide Free Anti-Mouse H-2Db antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, CMCD, and blocking assays.

niveau d'endotoxine: Low Endotoxin

Immunogène: C3H.SW mouse splenocytes

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Agent conservateur: Azide free

Conseil sur la manipulation: Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: 2-8°C

Détails sur H2-D1

Antigène: H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))

Autre désignation: H-2Db

Sujet: The 'classical' MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant β 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8 + T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8 + T cells during T cell ontogeny.

ID gène: 14964

UniProt: P01899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process