CD32/CD16 anticorps (APC)

N° du produit ABIN375786

Détail du produit anti-CD32/CD16 anticorps (APC)

Antigène: CD32/CD16

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD32/CD16 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Specificité: Mouse CD16/32

Attributs du produit: Rat Anti-Mouse CD16/32-APC

Purification: Purified

Immunogène: VH81X Tg B cells and T220 stromal cell line

Clone: 93

Isotype: IgG2a

Information d'application

Indications d'application:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 3 g/106 cells FITC and BIOT conjugates 3 g/106 cells PE, APC, SPRD, PE/CY5.5, and PE/CY7 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Commentaires:

Blocking of g receptors

Volume d'échantillon: 1 mL

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C

Détails sur CD32/CD16

Antigène: CD32/CD16

Autre désignation: CD16/32 (CD32/CD16 Produits)

Sujet: The lymphocyte Fc γ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc γ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying Fc γ R + cells, monoclonal antibodies to the Fc γ II/III receptor have been used to block Fc receptor binding of IgG, Fc- mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc γ R for parasitic invasion.