ITGA5 anticorps (Biotin)

N° du produit ABIN379959

Cet anticorps anti-ITGA5 Monoclonal Souris conjugué à Biotin (Clone X-6) (ABIN379959) détecte spécifiquement ITGA5 dans IHC et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITGA5 anticorps (Biotin) (ABIN379959)

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA5 est conjugé à/à la Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: X-6

Détail du produit anti-ITGA5 anticorps (Biotin)

Specificité: The antigen is a 154-180  kDa protein as determined by immunoprecipitation. The epitope has not been further characterized. Antigen distribution: Isolated cells: Granulocytes, monocytes, positive on blood monocyte-derived macrophages days 0-28. Dull staining with 95 % cord blood CD34+ cells, weak reaction on resting neutrophils. Staining increases with maturation of granulocytes. Treatment with fMLP, TNF, GM-CSF and temperature causes positive shift with granulocytes and monocytes. PMA treatment of granulocytes leads to a decrease in the number of positive cells. Positive with cell lines U937, DH39 & MEP, HL-60, NB4, HMC-1. Tissue sections: X-6 is positive on lining cells in different infiltrations and endothelial cells in the synovial membrane of rheumatoid arthritis patients. The staining pattern is similar to CD34 in these patients. Specificity: Human: granulocytes, monocytes, platelets. Other species: not tested.

Purification: Affinity purified

Immunogène: Human monocytes

Type of Immunogen: Cells

Information d'application

Indications d'application: Approved: IHC, IHC-Fr (1:100)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C.

Détails sur ITGA5

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Autre désignation: ITGA5/Integrin Alpha 5/CD49e

Sujet: Name/Gene ID: ITGA5
Family: Integrin

Synonyms: ITGA5, FNRA, Integrin alpha-5, Integrin Alpha 5, Integrin alpha-F, VLA-5, CD49e, CD49e antigen, VLA5A

ID gène: 3678

UniProt: P08648

Pathways: Integrin Complex