DNMT3A anticorps (AA 457-486)

N° du produit ABIN387882

Cité dans 2 publications. Cet anticorps anti-DNMT3A Polyclonal Lapin (Clone RB15269) (ABIN387882) détecte spécifiquement DNMT3A dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DNMT3A anticorps (AA 457-486) (ABIN387882)

Antigène: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT3A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15269

Détail du produit anti-DNMT3A anticorps

Épitope: AA 457-486

Homologie: C, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the Central region of human Dnmt3a.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-DNMT3A (ABIN387882)

Husni, Shiba-Ishii, Iiyama, Shiozawa, Kim, Nakagawa, Sato, Kano, Minami, Noguchi: "DNMT3a expression pattern and its prognostic value in lung adenocarcinoma." dans: Lung cancer (Amsterdam, Netherlands), Vol. 97, pp. 59-65, (2017) (PubMed).

Chestnut, Chang, Price, Lesuisse, Wong, Martin: "Epigenetic regulation of motor neuron cell death through DNA methylation." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 46, pp. 16619-36, (2011) (PubMed).

Détails sur DNMT3A

Antigène: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Autre désignation: Dnmt3a

Sujet: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Poids moléculaire: 101858

ID gène: 1788

NCBI Accession: NP_072046, NP_715640, NP_783328, NP_783329

UniProt: Q9Y6K1