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IFITM3 anticorps (N-Term)

IFITM3 Reactivité: Humain, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB13975 unconjugated
N° du produit ABIN387989
  • Antigène Voir toutes IFITM3 Anticorps
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    Épitope
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivité
    • 38
    • 5
    • 5
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 29
    • 6
    • 3
    Lapin
    Clonalité
    • 32
    • 6
    Polyclonal
    Conjugué
    • 26
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IFITM3 est non-conjugé
    Application
    • 28
    • 19
    • 11
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Interferon-inducible protein (IFITM3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Interferon-inducible protein (IFITM3).
    Clone
    RB13975
    Isotype
    Ig Fraction
  • Indications d'application
    IF: 1:100~500. WB: 1:1000. WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:100. IHC-P-Leica: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze-thaw cycles.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Date de péremption
    6 months
  • Savidis, Perreira, Portmann, Meraner, Guo, Green, Brass: "The IFITMs Inhibit Zika Virus Replication." dans: Cell reports, Vol. 15, Issue 11, pp. 2323-30, (2017) (PubMed).

    Mäkelä, Österlund, Westenius, Latvala, Diamond, Gale, Julkunen: "RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression." dans: Journal of virology, Vol. 89, Issue 23, pp. 12014-25, (2015) (PubMed).

    John, Chin, Perreira, Feeley, Aker, Savidis, Smith, Elia, Everitt, Vora, Pertel, Elledge, Kellam, Brass: "The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication." dans: Journal of virology, Vol. 87, Issue 14, pp. 7837-52, (2013) (PubMed).

    Everitt, Clare, Pertel, John, Wash, Smith, Chin, Feeley, Sims, Adams, Wise, Kane, Goulding, Digard, Anttila, Baillie, Walsh, Hume, Palotie, Xue, Colonna, Tyler-Smith, Dunning, Gordon, Smyth, Openshaw et al.: "IFITM3 restricts the morbidity and mortality associated with influenza. ..." dans: Nature, Vol. 484, Issue 7395, pp. 519-23, (2012) (PubMed).

    Feeley, Sims, John, Chin, Pertel, Chen, Gaiha, Ryan, Donis, Elledge, Brass: "IFITM3 inhibits influenza A virus infection by preventing cytosolic entry." dans: PLoS pathogens, Vol. 7, Issue 10, pp. e1002337, (2011) (PubMed).

    Brass, Huang, Benita, John, Krishnan, Feeley, Ryan, Weyer, van der Weyden, Fikrig, Adams, Xavier, Farzan, Elledge: "The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus." dans: Cell, Vol. 139, Issue 7, pp. 1243-54, (2010) (PubMed).

  • Antigène
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    Autre désignation
    Interferon-inducible protein (IFITM3) (IFITM3 Produits)
    Synonymes
    anticorps 1110004C05Rik, anticorps Cd225, anticorps Cdw217, anticorps DSPA2b, anticorps Fgls, anticorps IP15, anticorps mil-1, anticorps 1-8U, anticorps rat8, anticorps Interferon-induced transmembrane protein 3, anticorps interferon induced transmembrane protein 3, anticorps ifm3, anticorps Ifitm3, anticorps IFITM3
    Sujet
    The family of interferon-induced transmembrane protein (Ifitm/mil/fragilis) cell surface proteins may modulate cell adhesion and influence cell differentiation.
    Poids moléculaire
    14632
    ID gène
    10410
    NCBI Accession
    NP_066362
    UniProt
    Q01628
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