SUMO2/3 anticorps (AA 38-64)
Aperçu rapide pour SUMO2/3 anticorps (AA 38-64) (ABIN388032)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 38-64
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This SUMO2/3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-64 amino acids from the Central region of human SUMO2/3.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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Autre désignation
- SUMO2/3
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Sujet
- SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
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Poids moléculaire
- 11637
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ID gène
- 6612
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NCBI Accession
- NP_008867
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UniProt
- P55854
Antigène
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