BCL2A1 anticorps (Ala1)

N° du produit ABIN388092

Cet anticorps anti-BCL2A1 est un anticorps Lapin Polyclonal détectant BCL2A1 dans WB et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour BCL2A1 anticorps (Ala1) (ABIN388092)

Antigène: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1251

Détail du produit anti-BCL2A1 anticorps

Épitope: AA 30-65, Ala1

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BCL2A1 (A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-65 amino acids from human BCL2A1 (A1).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BCL2A1 (ABIN388092)

Gollob, Sciambi, Huang, Dressman: "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." dans: Cancer research, Vol. 65, Issue 19, pp. 8869-77, (2005) (PubMed).

Détails sur BCL2A1

Antigène: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Autre désignation: BCL2A1

Sujet: Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.

Poids moléculaire: 20132

ID gène: 597

NCBI Accession: NP_001108207, NP_004040

UniProt: Q16548