BIK anticorps (AA 39-74)

N° du produit ABIN388114

Détail du produit anti-BIK anticorps

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Épitope: AA 39-74

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-74 amino acids from human Bik BH3 Domain.

Clone: RB3381

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BIK (ABIN388114)

Sass, Shembade, Haimerl, Lamoureux, Hashemolhosseini, Tannapfel, Tiegs: "TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 10, pp. 7042-9, (2007) (PubMed).

Détails sur BIK

Antigène: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Autre désignation: Bik (BIK Produits)

Synonymes: anticorps BIK, anticorps Biklk, anticorps Blk, anticorps Nbk, anticorps BIP1, anticorps BP4, anticorps NBK, anticorps si:dkey-31f5.6, anticorps BCL2 interacting killer, anticorps BCL2-interacting killer, anticorps BCL2-interacting killer (apoptosis-inducing), anticorps BIK, anticorps Bik, anticorps bik

Sujet: The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.

Poids moléculaire: 18016

ID gène: 638

NCBI Accession: NP_001188

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity