HTRA1 anticorps (N-Term)

N° du produit ABIN2846341

Il existe 1 publication pour ce produit. L’anticorps anti-HTRA1 Polyclonal Lapin est utilisé pour la détection de HTRA1 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour HTRA1 anticorps (N-Term) (ABIN2846341)

Antigène: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTRA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB02326

Détail du produit anti-HTRA1 anticorps

Épitope: AA 116-147, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This HtrA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-147 amino acids from the N-terminal region of human HtrA1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IF: 1:10~50. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-HTRA1 (ABIN2846341)

Chamberland, Wang, Jones, Collins-Racie, LaVallie, Huang, Liu, Morris, Flannery, Yang: "Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo." dans: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27352-9, (2009) (PubMed).

Détails sur HTRA1

Antigène: HTRA1 (HtrA Serine Peptidase 1 (HTRA1))

Autre désignation: HtrA1

Sujet: HtrA1 a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.

Poids moléculaire: 51287

ID gène: 5654

NCBI Accession: NP_002766

UniProt: Q92743

Pathways: Growth Factor Binding