Cadherin 4 anticorps (N-Term)

N° du produit ABIN388148

Il existe 1 publication pour ce produit. L’anticorps anti-Cadherin 4 Polyclonal Lapin est utilisé pour la détection de Cadherin 4 dans des échantillons de Humain. Il a été validé pour WB, IF, FACS et IHC (p).

Aperçu rapide pour Cadherin 4 anticorps (N-Term) (ABIN388148)

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB13654

Détail du produit anti-Cadherin 4 anticorps

Épitope: AA 175-203, N-Term

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the N-terminal region of human CDH4.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Cadherin 4 (ABIN388148)

Li, Takai, Yuge, Furukawa, Tsuno, Tsukamoto, Kong, Moriyama, Narahara: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." dans: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: CDH4

Sujet: CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.

Poids moléculaire: 100281

ID gène: 1002

NCBI Accession: NP_001239267, NP_001239268, NP_001785

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size