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UBE2L6 anticorps (C-Term)

UBE2L6 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB4157 unconjugated
N° du produit ABIN388854
  • Antigène Voir toutes UBE2L6 Anticorps
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Épitope
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 123-153, C-Term
    Reactivité
    • 40
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 35
    • 6
    Lapin
    Clonalité
    • 38
    • 3
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBE2L6 est non-conjugé
    Application
    • 29
    • 21
    • 14
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.
    Clone
    RB4157
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Zhao, Sridharan, Chen, Baker, Wang, Krug: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." dans: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).

    Pietschmann, Buchwald, Müller, Knauer, Kögl, Heinzel, Krämer: "Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1." dans: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 132-8, (2011) (PubMed).

    Krämer, Müller, Buchwald, Reichardt, Heinzel: "Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1369-79, (2008) (PubMed).

  • Antigène
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Autre désignation
    UBE2L6 (UBE2L6 Produits)
    Synonymes
    anticorps UBE2L6, anticorps RIG-B, anticorps UBCH8, anticorps 2810489I21Rik, anticorps Ubce8, anticorps Ubcm8, anticorps UbcM8, anticorps ubiquitin conjugating enzyme E2 L6, anticorps ubiquitin-conjugating enzyme E2L 6, anticorps UBE2L6, anticorps Ube2l6
    Sujet
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
    Poids moléculaire
    17769
    ID gène
    9246
    NCBI Accession
    NP_004214, NP_937826
    UniProt
    O14933
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