Ubiquilin 1 anticorps (N-Term)

N° du produit ABIN388971

Cet anticorps anti-Ubiquilin 1 est un anticorps Lapin Polyclonal détectant Ubiquilin 1 dans WB et IHC (p). Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Ubiquilin 1 anticorps (N-Term) (ABIN388971)

Antigène: Ubiquilin 1 (UBQLN1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ubiquilin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4615

Détail du produit anti-Ubiquilin 1 anticorps

Épitope: AA 19-49, N-Term

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Ubiquilin1 (PLIC1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human Ubiquilin1 (PLIC1).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Ubiquilin 1 (ABIN388971)

Sick, Boukhari, Deramaudt, Rondé, Bucher, André, Gies, Takeda: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." dans: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).

Détails sur Ubiquilin 1

Antigène: Ubiquilin 1 (UBQLN1)

Autre désignation: Ubiquilin1 (PLIC1)

Sujet: PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.

Poids moléculaire: 62519

ID gène: 29979

NCBI Accession: NP_038466, NP_444295

UniProt: Q9UMX0