Ubiquilin 1 anticorps (N-Term)

N° du produit ABIN388971

Détail du produit anti-Ubiquilin 1 anticorps

Antigène: Ubiquilin 1 (UBQLN1)

Épitope: AA 19-49, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ubiquilin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Ubiquilin1 (PLIC1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human Ubiquilin1 (PLIC1).

Clone: RB4615

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Ubiquilin 1 (ABIN388971)

Sick, Boukhari, Deramaudt, Rondé, Bucher, André, Gies, Takeda: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." dans: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).

Détails sur Ubiquilin 1

Antigène: Ubiquilin 1 (UBQLN1)

Autre désignation: Ubiquilin1 (PLIC1) (UBQLN1 Produits)

Synonymes: anticorps UBQLN1, anticorps DA41, anticorps DSK2, anticorps PLIC-1, anticorps UBQN, anticorps XDRP1, anticorps 1110046H03Rik, anticorps 1810030E05Rik, anticorps AU019746, anticorps C77538, anticorps D13Ertd372e, anticorps Da41, anticorps Dsk2, anticorps Plic-1, anticorps Plic1, anticorps Xdrp1, anticorps ubiquilin 1, anticorps UBQLN1, anticorps Ubqln1

Sujet: PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.

Poids moléculaire: 62519

ID gène: 29979

NCBI Accession: NP_038466, NP_444295

UniProt: Q9UMX0