GGPS1 anticorps (N-Term)

N° du produit ABIN389055

Détail du produit anti-GGPS1 anticorps

Antigène: GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

Épitope: AA 16-46, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GGPS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human GGPS1.

Clone: RB4788

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GGPS1 (ABIN389055)

Iguchi, Katsuno, Niwa, Yamada, Sone, Waza, Adachi, Tanaka, Nagata, Arimura, Watanabe, Kaibuchi, Sobue: "TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases." dans: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22059-66, (2009) (PubMed).

Détails sur GGPS1

Antigène: GGPS1 (Geranylgeranyl Diphosphate Synthase 1 (GGPS1))

Autre désignation: GGPS1 (GGPS1 Produits)

Synonymes: anticorps geranylgeranyl pyrophosphate synthase 1, anticorps DDBDRAFT_0192027, anticorps DDBDRAFT_0233098, anticorps DDB_0192027, anticorps DDB_0233098, anticorps GGPPS, anticorps GGPPS1, anticorps 1810026C22Rik, anticorps 9530089B04Rik, anticorps AI843169, anticorps C79210, anticorps Crlf3, anticorps rGGPS1a, anticorps rGGPS1a1, anticorps rGGPS1a2, anticorps rGGPS1a3, anticorps fb05f09, anticorps qm, anticorps wu:fb05f09, anticorps zgc:101591, anticorps zgc:56514, anticorps geranylgeranyl pyrophosphate synthase 1, anticorps geranylgeranyl pyrophosphate synthetase, anticorps geranyl pyrophosphate synthase, anticorps geranylgeranyl pyrophosphate synthase,chloroplastic, anticorps geranylgeranyl diphosphate synthase 1, anticorps geranylgeranyl diphosphate synthase 1 L homeolog, anticorps GGPS1, anticorps gGPS1, anticorps ggps1, anticorps Ggps1, anticorps ggps1.L

Sujet: Geranylgeranyl diphosphate (GGPP) synthase (GGPS) catalyzes the synthesis of GGPP, a molecule responsible for the C20-prenylation of protein and for the regulation of a nuclear hormone receptor. The deduced 300-amino acid human protein contains 5 conserved domains consistent with prenyltransferases. Recombinant GGPS shows enzymatic properties associated with the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. Mouse GGPS is regulated in several tissues in obesity and is induced during adipocyte differentiation. GGPS is increased 5- to 20-fold in skeletal muscle, liver, and fat of ob/ob mice. Western blot analysis detects a 2-fold overexpression of protein in muscle and fat but not in liver. Differentiation of mouse fibroblasts into adipocytes induces GGPS expression more than 20-fold.

Poids moléculaire: 34871

ID gène: 9453

NCBI Accession: NP_001032354

UniProt: O95749