ACOX1 anticorps (N-Term)

N° du produit ABIN389099

L’anticorps Lapin Polyclonal anti-ACOX1 a été validé pour IHC (p). Il convient pour détecter ACOX1 dans des échantillons de Humain et Souris. Il y a 1 publication disponible.

Aperçu rapide pour ACOX1 anticorps (N-Term) (ABIN389099)

Antigène: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACOX1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB04649

Détail du produit anti-ACOX1 anticorps

Épitope: AA 7-37, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human ACOX1.

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ACOX1 (ABIN389099)

Bagattin, Hugendubler, Mueller: "Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 47, pp. 20376-81, (2010) (PubMed).

Détails sur ACOX1

Antigène: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Autre désignation: ACOX1

Sujet: ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Poids moléculaire: 74424

ID gène: 51

NCBI Accession: NP_001171968, NP_004026, NP_009223

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process