APRT anticorps (C-Term)

N° du produit ABIN389427

Cet anticorps anti-APRT est un anticorps Lapin Polyclonal détectant APRT dans WB et IHC (p). Adapté pour Humain et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour APRT anticorps (C-Term) (ABIN389427)

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APRT est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20510

Détail du produit anti-APRT anticorps

Épitope: AA 143-170, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-APRT (ABIN389427)

Valaperta, Rizzo, Lombardi, Verdelli, Piccoli, Ghiroldi, Creo, Colombo, Valisi, Margiotta, Panella, Costa: "Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation." dans: BMC nephrology, Vol. 15, pp. 102, (2014) (PubMed).

Détails sur APRT

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Autre désignation: APRT

Sujet: A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.

Poids moléculaire: 19608

ID gène: 353

NCBI Accession: NP_000476, NP_001025189

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process