IMMT anticorps (AA 438-467)

N° du produit ABIN389477

L’anticorps Lapin Polyclonal anti-IMMT a été validé pour WB, FACS et IHC (p). Il convient pour détecter IMMT dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour IMMT anticorps (AA 438-467) (ABIN389477)

Antigène: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IMMT est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20815

Détail du produit anti-IMMT anticorps

Épitope: AA 438-467

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This IMMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human IMMT.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-IMMT (ABIN389477)

Steffen, Vashisht, Wan, Jen, Claypool, Wohlschlegel, Koehler: "Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria." dans: Molecular biology of the cell, Vol. 28, Issue 5, pp. 600-612, (2017) (PubMed).

Détails sur IMMT

Antigène: IMMT (Inner Membrane Protein, Mitochondrial (IMMT))

Autre désignation: IMMT

Sujet: Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.

Poids moléculaire: 83678

ID gène: 10989

NCBI Accession: NP_001093639, NP_001093640, NP_006830

UniProt: Q16891