BIRC7 anticorps (C-Term)

N° du produit ABIN390073

Cet anticorps Lapin Polyclonal détecte spécifiquement BIRC7 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BIRC7 anticorps (C-Term) (ABIN390073)

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1799-1800

Détail du produit anti-BIRC7 anticorps

Épitope: AA 271-298, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BIRC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-298 amino acids from the C-terminal region of human BIRC7.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur BIRC7

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Autre désignation: BIRC7

Sujet: BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Poids moléculaire: 32798

ID gène: 79444

NCBI Accession: NP_071444, NP_647478

UniProt: Q96CA5