MLLT1 anticorps (C-Term)

N° du produit ABIN390126

Cité dans 1 publication. Cet anticorps anti-MLLT1 Polyclonal Lapin (Clone RB1927-1928) (ABIN390126) détecte spécifiquement MLLT1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MLLT1 anticorps (C-Term) (ABIN390126)

Antigène: MLLT1 (MLLT1, super elongation complex subunit (MLLT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLLT1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB1927-1928

Détail du produit anti-MLLT1 anticorps

Épitope: AA 523-552, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MLLT1 (ABIN390126)

Bitoun, Oliver, Davies: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." dans: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).

Détails sur MLLT1

Antigène: MLLT1 (MLLT1, super elongation complex subunit (MLLT1))

Autre désignation: MLLT1

Sujet: Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.

Poids moléculaire: 62056

ID gène: 4298

NCBI Accession: NP_005925

UniProt: Q03111